Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598576 | 0.89 | MEN1 (0.45) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL18720922 | 0.81 | LMNA (0.48) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL23867079 | 0.80 | LMNA (0.62) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL21989948 | 0.80 | MEN1 (0.44) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL5605601 | 0.79 | LMNA (0.46) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL30979277 | 0.79 | LMNA (0.46) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL23522266 | 0.79 | LMNA (0.46) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL23522267 | 0.79 | LMNA (0.46) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL4579218 | 0.79 | LMNA (0.46) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL7864089 | 0.79 | LMNA (0.46) | MEN1CYP3A4ALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461072-B1 | Process for the preparation of polyurethanes using specific stabilizer systems | CIBA GEIGY AG (CH) | 1998-07-29 | — | — | EP | disclosed |
| US-5077321-A | Using two structurally different stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0461072-A2 | Process for the preparation of polyurethanes using specific stabilizer systems | CIBA-GEIGY AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| EP-0428973-A1 | Mixtures of stabilisers for elastomers | CIBA-GEIGY AG (CH) | 1991-05-29 | — | — | EP | disclosed |