Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118442 | 1.00 | GABRA1 (0.54) | GABRA1GABRB2TSHRGABRG2GABRB3 | |
| SCHEMBL6681972 | 0.82 | GABRA1 (0.52) | GABRA1GABRB2TSHRGABRG2GABRB3 | |
| SCHEMBL9184834 | 0.82 | GABRA1 (0.52) | GABRA1GABRB2TSHRGABRG2GABRB3 | |
| SCHEMBL20801133 | 0.80 | GABRA1 (0.34) | GABRA1GABRB2TSHRGABRG2GABRB3 | |
| SCHEMBL3931197 | 0.80 | GABRA1 (0.44) | GABRA1GABRB2TSHRCYP3A4LMNA | |
| SCHEMBL31247924 | 0.80 | GABRA1 (0.44) | GABRA1GABRB2TSHRCYP3A4LMNA | |
| SCHEMBL3678783 | 0.80 | GABRA1 (0.44) | GABRA1GABRB2TSHRCYP3A4LMNA | |
| SCHEMBL13660579 | 0.80 | GABRA1 (0.44) | GABRA1GABRB2TSHRCYP3A4LMNA | |
| SCHEMBL1561218 | 0.80 | GABRA1 (0.45) | GABRA1GABRB2TSHRGABRG2GABRB3 | |
| Hydrogen Peroxide SCHEMBL5685702 | 0.79 | GABRA1 (0.65) | GABRA1GABRB2TRPA1LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1029679-C | Method for producing ibuprofen | HOECHST CELANESE CORP (US) | 1995-09-06 | — | — | CN | claimed |
| CN-88102150-A | METHOD FOR PRODUCING IBUPROFEN | — | 1988-11-23 | — | — | CN | claimed |
| JP-3191796-A | — | — | None | — | — | JP | disclosed |
| JP-1311043-A | — | — | None | — | — | JP | disclosed |
| CN-112955250-B | Method and device for carrying out chemical reactions under elevated pressure | 巴斯夫欧洲公司 | 2024-06-11 | — | — | CN | disclosed |
| US-11850578-B2 | Method and apparatus for performing a chemical reaction under elevated pressure | BASF SE (DE) | 2023-12-26 | — | — | US | disclosed |
| US-20210322941-A1 | METHOD AND APPARATUS FOR PERFORMING A CHEMICAL REACTION UNDER ELEVATED PRESSURE | BASF SE (DE) | 2021-10-21 | — | — | US | disclosed |
| EP-3852914-A1 | METHOD AND APPARATUS FOR PERFORMING A CHEMICAL REACTION UNDER ELEVATED PRESSURE | BASF SE (DE) | 2021-07-28 | — | — | EP | disclosed |
| CN-112955250-A | Method and apparatus for conducting chemical reactions at elevated pressures | 巴斯夫欧洲公司 | 2021-06-11 | — | — | CN | disclosed |
| WO-2020058283-A1 | METHOD AND APPARATUS FOR PERFORMING A CHEMICAL REACTION UNDER ELEVATED PRESSURE | BASF SE (DE) | 2020-03-26 | — | — | WO | disclosed |
| US-9358191-B2 | Deodorant composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2016-06-07 | — | — | US | disclosed |
| CN-1029679-C | Method for producing ibuprofen | HOECHST CELANESE CORP (US) | 1995-09-06 | — | — | CN | disclosed |
| JP-H03191796-A | PRODUCTION OF OPTICALLY ACTIVE 1-PARA-ISOBUTYLPHENYLETHANOL AND ITS CARBOXYLIC ACID ESTER | DAICEL CHEM IND LTD | 1991-08-21 | — | — | JP | disclosed |
| JP-H01311043-A | PROCESS FOR RECYCING CATALYST IN CARBONYLATION OF ISOBUTYLPHENYL ETHANOL INTO IBUPROFEN | HOECHST CELANESE CORP | 1989-12-15 | — | — | JP | disclosed |
| EP-0337803-A1 | Catalyst recycle in the carbonylation of isobutylphenylethanol to ibuprofen | HOECHST CELANESE CORPORATION (US) | 1989-10-18 | — | — | EP | disclosed |
| EP-0337803-A1 | Catalyst recycle in the carbonylation of isobutylphenylethanol to ibuprofen | HOECHST CELANESE CORPORATION (US) | 1989-10-18 | — | — | EP | disclosed |
| EP-0337803-A1 | Catalyst recycle in the carbonylation of isobutylphenylethanol to ibuprofen | HOECHST CELANESE CORPORATION (US) | 1989-10-18 | — | — | EP | disclosed |
| CN-88102150-A | METHOD FOR PRODUCING IBUPROFEN | — | 1988-11-23 | — | — | CN | disclosed |
| US-4601797-A | Electrochemical carboxylation of p-isobutylacetophenone and other aryl ketones | MONSANTO COMPANY (US) | 1986-07-22 | — | — | US | disclosed |
| US-4582577-A | Electrochemical carboxylation of p-isobutylacetophenone | MONSANTO COMPANY (US) | 1986-04-15 | — | — | US | disclosed |