SCHEMBL8736944

SCHEMBL8736944

CC1(C)c2ccccc2-c2ccc(-c3cc(-c4cccc(-c5cccc(-c6nc(-c7ccccc7)cc(-c7ccccc7)n6)c5)c4)cc(-n4c5ccccc5c5ccccc54)c3)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 7/20 0.34
▸ KMT2A Q03164 7/20 0.34
▸ MAPT P10636 6/20 0.34
▸ ALDH1A1 P00352 5/20 0.34
▸ HPGD P15428 5/20 0.34
▸ KDM4E B2RXH2 4/20 0.34
▸ LMNA P02545 3/20 0.34
▸ NTSR1 P30989 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ PDK2 Q15119 6/20 0.32
▸ ATM Q13315 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ FLT3 P36888 2/20 0.32
▸ CYP2C19 P33261 2/20 0.31
▸ ACACA Q13085 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ RXFP1 Q9HBX9 1/20 0.31
▸ CYP1A2 P05177 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ MAPK10 P53779 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8735664 1.00 MEN1 (0.34) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8734604 0.97 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8735666 0.97 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8735461 0.97 MEN1 (0.34) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8736114 0.96 MEN1 (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8734611 0.96 MEN1 (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8734563 0.96 MEN1 (0.33) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8736549 0.96 MEN1 (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8736975 0.96 PDK2 (0.34) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8735667 0.96 PDK2 (0.34) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266851-B2 Fluorene-containing aromatic compound, material for organic electroluminescent element, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-23 — — US disclosed
US-9266851-B2 Fluorene-containing aromatic compound, material for organic electroluminescent element, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-23 — — US disclosed
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO. LTD. (JP) 2012-05-24 — — US disclosed
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO. LTD. (JP) 2012-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME NR0B2, AFF2, AFF1 MEN1 2878/4885KMT2A 563/4885MAPT 2854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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