Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.50 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430077 | 0.86 | ABCC4 (0.39) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL13347365 | 0.86 | ABCC4 (0.39) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL3112944 | 0.81 | CACNA2D1 (0.59) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL3116772 | 0.81 | CACNA2D1 (0.59) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL1913688 | 0.81 | CACNA2D1 (0.59) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL16429594 | 0.80 | ABCC4 (0.35) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL563220 | 0.78 | ABCC4 (0.34) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL24653140 | 0.78 | CACNA2D1 (0.65) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL7907883 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL563740 | 0.77 | GRIK1 (0.33) | CACNA2D1CACNB3CACNA1CPGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009560-A1 | GABA AND L-GLUTAMIC ACID ANALOGS FOR ANTISEIZURE TREATMENT | NORTHWESTERN UNIVERSITY (US) | 1992-06-11 | — | — | WO | claimed |
| US-9925204-B2 | Anti-inflammatory compounds in combination with hydrogen for the treatment of inflammation | KAWAI TOSHIHISA (US) | 2018-03-27 | — | — | US | disclosed |
| US-9545415-B2 | Anti-inflammatory compounds in combination with hydrogen for the treatment of inflammation | SKYVIEW ENTPR LTD (US) | 2017-01-17 | — | — | US | disclosed |
| US-20160317575-A1 | ANTI-INFLAMMATORY COMPOUNDS IN COMBINATION WITH HYDROGEN FOR THE TREATMENT OF INFLAMMATION | KAWAI TOSHIHISA (US) | 2016-11-03 | — | — | US | disclosed |
| US-20150140090-A1 | ANTI-INFLAMMATORY COMPOUNDS IN COMBINATION WITH HYDROGEN FOR THE TREATMENT OF INFLAMMATION | SKYVIEW ENTPR LTD (US) | 2015-05-21 | — | — | US | disclosed |
| EP-0934061-B3 | ISOBUTYLGABA AND ITS DERIVATIVES FOR THE TREATMENT OF PAIN | WARNER LAMBERT CO (US) | 2015-01-21 | — | — | EP | disclosed |
| CN-102459169-B | Redox drug derivatives | REDX PHARMA LTD | 2014-12-31 | — | — | CN | disclosed |
| US-8877945-B2 | Redox drug derivatives | REDX PHARMA LIMITED (GB) | 2014-11-04 | — | — | US | disclosed |
| EP-2429991-B1 | REDOX DRUG DERIVATIVES | REDX PHARMA LTD (GB) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013103826-A1 | ANTI-INFLAMMATORY COMPOUNDS IN COMBINATION WITH HYDROGEN FOR THE TREATMENT OF INFLAMMATION | SKYVIEW ENTERPRISE LTD. (US) | 2013-07-11 | — | — | WO | disclosed |
| WO-1998003167-A1 | ISOBUTYLGABA AND ITS DERIVATIVES FOR THE TREATMENT OF PAIN | WARNER-LAMBERT COMPANY (US) | 1998-01-29 | — | — | WO | disclosed |
| US-5710304-A | 5-METHYL-3((((4-METHYLPHENYL)SULFONYL)OXY)-METHYL)-HEXANOIC ACID ESTER CHEMICAL INTERMEDIATES | NORTHWESTERN UNIVERSITY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5684189-A | HYDROLYZING AN AZIDE TO FORM AN INTERMEDIATE AZIDE, EXTRACTING THE INTERMEDIATE AZIDE INTO AN AQUEOUS BASE AND REDUCING THE AZIDE TO AN AMINE | NORTHWESTERN UNIVERSITY (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0641330-A4 | GABA AND L-GLUTAMIC ACID ANALOGS FOR ANTISEIZURE TREATMENT. | UNIV NORTHWESTERN (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5608090-A | ANTICONVULSANTS | NORTHWESTERN UNIVERSITY (US) | 1997-03-04 | — | — | US | disclosed |
| US-5599973-A | REACTING ACID CHLORIDE WITH SUBSTITUTED 2-OXAZOLIDINONE AND BUTYLLITHIUM, THEN BENZYL ALPHA-BROMOACETATE, HYDROGEN PEROXIDE, LITHIUM OXIDE, SODIUM METABISULFITE, BORANE DIMETHYL SULFIDE, THEN TOSYLATION, AZIDE FORMATION, AMINATION | NORTHWESTERN UNIVERSITY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5563175-A | GAMMAAMINOBUTYRIC ACID DERIVATIVE; NERVOUS SYSTEM DISORDERS | NORTHWESTERN UNIVERSITY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0641330-A1 | GABA AND L-GLUTAMIC ACID ANALOGS FOR ANTISEIZURE TREATMENT | NORTHWESTERN UNIVERSITY (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993023383-A1 | GABA AND L-GLUTAMIC ACID ANALOGS FOR ANTISEIZURE TREATMENT | NORTHWESTERN UNIVERSITY (US) | 1993-11-25 | — | — | WO | disclosed |
| WO-1992009560-A1 | GABA AND L-GLUTAMIC ACID ANALOGS FOR ANTISEIZURE TREATMENT | NORTHWESTERN UNIVERSITY (US) | 1992-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160317575-A1 | ANTI-INFLAMMATORY COMPOUNDS IN COMBINATION WITH HYDROGEN FOR THE TREATMENT OF INFLAMMATION | PTGS1, HVCN1, HRH2 | CACNA2D1 1262/4885CACNB3 581/4885CACNA1C 331/4885 |
| US-20150140090-A1 | ANTI-INFLAMMATORY COMPOUNDS IN COMBINATION WITH HYDROGEN FOR THE TREATMENT OF INFLAMMATION | PTGS1, HVCN1, HRH2 | CACNA2D1 1262/4885CACNB3 581/4885CACNA1C 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.