Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.47 |
| ▸ | TYR | P14679 | 3/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675385 | 0.82 | ESR1 (0.54) | ESR1ESR2TYRNR1H2NR1H3 | |
| SCHEMBL8737327 | 0.80 | ESR1 (0.47) | ESR1ESR2TYRNR1H2NR1H3 | |
| SCHEMBL31621158 | 0.77 | KLF10 (0.62) | ESR1ESR2TYRKLF10MEN1 | |
| SCHEMBL673962 | 0.77 | CYP2D6 (0.57) | ESR1ESR2TYRKLF10MEN1 | |
| SCHEMBL5082027 | 0.77 | KLF10 (0.62) | ESR1ESR2TYRKLF10MEN1 | |
| SCHEMBL1269961 | 0.74 | ESR1 (0.53) | ESR1ESR2TYRKLF10MEN1 | |
| SCHEMBL19436821 | 0.74 | ESR1 (0.53) | ESR1ESR2TYRKLF10MEN1 | |
| SCHEMBL15539985 | 0.74 | TYR (0.42) | ESR1ESR2TYRMEN1TP53 | |
| SCHEMBL27997840 | 0.73 | ESR1 (0.55) | ESR1ESR2TYRKLF10CYP3A4 | |
| SCHEMBL31296234 | 0.72 | ESR1 (0.48) | ESR1ESR2TYRKLF10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833857-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000906-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1997-01-09 | — | — | WO | disclosed |