Pyridine

Pyridine

SCHEMBL873759

CS(=O)(=O)Cl.c1ccncc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.53
NAPRT Q6XQN6 2/20 0.53
TSHR P16473 1/20 0.53
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL431430 0.88 TDP1 (0.60) TDP1NAPRTTSHRALDH1A1HSD17B10
Benzene SCHEMBL19063434 0.88 TDP1 (0.60) TDP1NAPRTTSHRALDH1A1HSD17B10
Pyridine SCHEMBL6742447 0.85 TDP1 (0.56) TDP1NAPRTTSHRALDH1A1HSD17B10
Pyridine SCHEMBL28738366 0.85 TDP1 (0.56) TDP1NAPRTTSHRALDH1A1HSD17B10
Pyridine SCHEMBL4778534 0.85 TDP1 (0.56) TDP1NAPRTTSHRALDH1A1HSD17B10
Pyridine SCHEMBL1819960 0.83 TDP1 (0.47) TDP1NAPRTTSHRALDH1A1HSD17B10
Pyridine SCHEMBL10678990 0.82 NAPRT (0.53) TDP1NAPRTTSHRALDH1A1
Pyridine SCHEMBL27323193 0.82 NAPRT (0.53) TDP1NAPRTTSHR
Pyridine SCHEMBL28192777 0.82 NAPRT (0.53) TDP1NAPRTTSHRALDH1A1
Pyridine SCHEMBL546119 0.82 NAPRT (0.53) TDP1NAPRTTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023098650-A1 ANTIVIRAL USE OF BISEPOXYLIGNAN COMPOUND, AND BISEPOXYLIGNAN COMPOSITION AND PREPARATION OF BISEPOXYLIGNAN COMPOUND 盖鑫 2023-06-08 WO claimed
CN-116196321-A Application and preparation of bisepoxylignanoid compound and antiviral composition 盖鑫 2023-06-02 CN claimed
US-8552219-B2 Process for preparing L-phenyl-3-dimethylaminopropane derivative IND-SWIFT LABORATORIES LIMITED (IN) 2013-10-08 US claimed
EP-2619174-A1 PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE Ind-Swift Laboratories Limited (IN) 2013-07-31 EP claimed
US-20130190522-A1 PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE IND-SWIFT LABORATORIES LIMITED (IN) 2013-07-25 US claimed
WO-2012038974-A1 PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE IND-SWIFT LABORATORIES LIMITED (IN) 2012-03-29 WO claimed
WO-2023098650-A1 ANTIVIRAL USE OF BISEPOXYLIGNAN COMPOUND, AND BISEPOXYLIGNAN COMPOSITION AND PREPARATION OF BISEPOXYLIGNAN COMPOUND 盖鑫 2023-06-08 WO disclosed
CN-116196321-A Application and preparation of bisepoxylignanoid compound and antiviral composition 盖鑫 2023-06-02 CN disclosed
CN-114934286-A Method for electrocatalytic carboxylic acid cyanidation 中国农业大学 2022-08-23 CN disclosed
CN-113087763-A Method for preparing cytotoxic benzodiazepine derivatives 伊缪诺金公司 2021-07-09 CN disclosed
CN-113004288-A Method for preparing cytotoxic benzodiazepine derivatives 伊缪诺金公司 2021-06-22 CN disclosed
CN-108026103-B Method for preparing cytotoxic benzodiazepine derivatives 伊缪诺金公司 2021-04-16 CN disclosed
CN-108290895-B Process for preparing cytotoxic benzodiazepine derivatives 伊缪诺金公司 2021-03-19 CN disclosed
CN-1092413-A The phenyloxazolidinone antibacterial agents that tropone replaces UPJOHN CO (US) 1994-09-21 CN disclosed
EP-0610265-A1 SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS. UPJOHN CO (US) 1994-08-17 EP disclosed
WO-1994013649-A1 TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS THE UPJOHN COMPANY (US) 1994-06-23 WO disclosed
WO-1993023400-A1 PENTACYCLIC ANTIHISTAMINES SCHERING CORPORATION (US) 1993-11-25 WO disclosed
CN-87105345-A Tertiary amine compound 1988-02-03 CN disclosed
US-3987082-A PROSTAGLANDIN INTERMEDIATE MERCK & CO., INC. (US) 1976-10-19 US disclosed
US-3950359-A PROSTAGLANDINS AND METHODS OF MAKING SAME MERCK & CO., INC. (US) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130190522-A1 PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE CYP3A43, UGT1A1, UGT1A7 TDP1 1658/4885NAPRT 2225/4885TSHR 4138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.