Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171678 | 0.80 | ALDH1A1 (0.37) | ALDH1A1GLAL3MBTL1KDM4EALDH2 | |
| SCHEMBL9918234 | 0.77 | MAOB (0.37) | ALDH1A1GLAL3MBTL1KDM4EALDH2 | |
| SCHEMBL19592355 | 0.76 | ALDH1A1 (0.35) | ALDH1A1GLAL3MBTL1KDM4EALDH2 | |
| SCHEMBL19592356 | 0.74 | ALDH1A1 (0.34) | ALDH1A1GLAL3MBTL1KDM4EALDH2 | |
| SCHEMBL9918862 | 0.72 | MAOB (0.35) | ALDH1A1GLAL3MBTL1KDM4EALDH2 | |
| SCHEMBL24595040 | 0.69 | ALDH1A1 (0.40) | ALDH1A1GLAL3MBTL1KDM4EALDH2 | |
| SCHEMBL16954255 | 0.66 | GLA (0.46) | ALDH1A1GLAL3MBTL1KDM4EGAA | |
| SCHEMBL16957324 | 0.66 | GLA (0.43) | ALDH1A1GLAL3MBTL1KDM4EHPGD | |
| SCHEMBL9921725 | 0.66 | KDM4E (0.37) | ALDH1A1GLAL3MBTL1KDM4EALDH2 | |
| SCHEMBL12041228 | 0.65 | GLA (0.48) | ALDH1A1GLAL3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455382-A1 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | Incyte Corporation (US) | 2012-05-23 | — | — | EP | disclosed |