Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2328953 | 0.95 | MEN1 (0.48) | TAAR1HRH3MEN1USP2ALDH1A1 | |
| SCHEMBL2332173 | 0.90 | MEN1 (0.55) | TAAR1HRH3MEN1USP2ALDH1A1 | |
| SCHEMBL2325119 | 0.90 | MEN1 (0.55) | TAAR1HRH3MEN1USP2ALDH1A1 | |
| SCHEMBL6568884 | 0.89 | TAAR1 (0.62) | TAAR1MAOB | |
| SCHEMBL11764067 | 0.87 | LTA4H (0.50) | TAAR1HRH3MAOBLTA4H | |
| SCHEMBL23291313 | 0.84 | TAAR1 (0.56) | TAAR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL23291137 | 0.84 | TAAR1 (0.56) | TAAR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL23928162 | 0.84 | TAAR1 (0.56) | TAAR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL21245437 | 0.84 | TAAR1 (0.56) | TAAR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL23291231 | 0.84 | TAAR1 (0.56) | TAAR1MEN1USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | The Regents of the University of Michigan (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040527-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-03-29 | — | — | WO | disclosed |