⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302372 | 0.84 | KDM4E (0.43) | — | |
| SCHEMBL7594795 | 0.79 | — | — | |
| SCHEMBL12092123 | 0.77 | — | — | |
| SCHEMBL26304773 | 0.75 | — | — | |
| SCHEMBL6323330 | 0.73 | ALDH1A1 (0.44) | — | |
| SCHEMBL925848 | 0.70 | — | — | |
| SCHEMBL8830985 | 0.70 | — | — | |
| SCHEMBL9375286 | 0.70 | — | — | |
| Bromide SCHEMBL5507726 | 0.69 | — | — | |
| SCHEMBL7524425 | 0.69 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695240-B2 | Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds | GENENTECH, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20150051380-A1 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | GENENTECH, INC. (US) | 2015-02-19 | — | — | US | disclosed |
| US-8900589-B2 | Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds | GENETECH, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8389697-B2 | Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds | GENENTECH, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120130059-A1 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | BERIA ITALO (IT) | 2012-05-24 | — | — | US | disclosed |
| US-20120130059-A1 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | BERIA ITALO (IT) | 2012-05-24 | — | — | US | disclosed |
| US-20100034837-A1 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | GENENTECH, INC. | 2010-02-11 | — | — | US | disclosed |