Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8227328 | 0.87 | APOBEC3G (0.51) | APOBEC3GGFERLMNATDP1CA9 | |
| SCHEMBL8233155 | 0.83 | APOBEC3G (0.68) | APOBEC3GGFERLMNATDP1CA9 | |
| SCHEMBL8235502 | 0.83 | APOBEC3G (0.47) | APOBEC3GGFERLMNATDP1CA9 | |
| SCHEMBL8232792 | 0.82 | APOBEC3G (0.48) | APOBEC3GGFERLMNATDP1CA9 | |
| SCHEMBL16542299 | 0.81 | APOBEC3G (0.45) | APOBEC3GGFERLMNATDP1CA9 | |
| SCHEMBL165618 | 0.77 | APOBEC3G (0.44) | APOBEC3GGFERLMNATDP1CA9 | |
| SCHEMBL8233143 | 0.77 | ALDH1A1 (0.58) | APOBEC3GGFERLMNATDP1CA9 | |
| Water SCHEMBL2512796 | 0.76 | APOBEC3G (0.43) | APOBEC3GGFERLMNATDP1CA9 | |
| SCHEMBL19265137 | 0.74 | AVPR2 (0.48) | APOBEC3GGFERLMNATDP1CA9 | |
| SCHEMBL4270680 | 0.74 | APOBEC3G (0.61) | APOBEC3GGFERLMNATDP1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027096-B1 | SUBSTITUTED ARYLIMIDAZ0L0NE AND TRIAZ0L0NE AS INHIBITORS OF VASOPRESSIN RECEPTORS | Bayer Pharma AG (DE) | 2012-05-23 | — | — | EP | disclosed |