Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10041893 | 1.00 | SLC6A4 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL10041925 | 0.98 | SLC6A4 (0.33) | SLC6A4SLC6A3 | |
| SCHEMBL10041863 | 0.98 | SLC6A4 (0.33) | SLC6A4SLC6A3 | |
| SCHEMBL15997118 | 0.98 | SLC6A4 (0.33) | SLC6A4SLC6A3 | |
| SCHEMBL8738179 | 0.84 | SLC6A4 (0.35) | SLC6A4SLC6A3 | |
| SCHEMBL14157766 | 0.83 | IDO1 (0.35) | SLC6A3 | |
| SCHEMBL14157753 | 0.82 | SLC6A4 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL10041858 | 0.81 | ALDH1A1 (0.35) | — | |
| SCHEMBL14156851 | 0.81 | ALDH1A1 (0.35) | — | |
| SCHEMBL3307691 | 0.80 | SLC6A4 (0.40) | SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455369-B1 | Derivatives of 2-aryl-4-quinolones having an aminoalkyl group as anticancer agents | UNIV CHINA MEDICAL (TW) | 2014-09-03 | — | — | EP | disclosed |
| EP-2096924-B1 | NOVEL HYDROPHILIC DERIVATIVES OF 2-ARYL-4-QUINOLONES AS ANTICANCER AGENTS | UNIV CHINA MEDICAL (TW) | 2013-02-13 | — | — | EP | disclosed |
| EP-2468747-A1 | 2-Selenophene-4-quinolones as anticancer agents | China Medical University (TW) | 2012-06-27 | — | — | EP | disclosed |
| EP-2455369-A1 | Derivatives of 2-aryl-4-quinolones having an aminoalkyl group as anticancer agents | China Medical University (TW) | 2012-05-23 | — | — | EP | disclosed |
| WO-2008070176-A1 | NOVEL HYDROPHILIC DERIVATIVES OF 2-ARYL-4-QUINOLONES AS ANTICANCER AGENTS | CHINA MEDICAL UNIVERSITY (TW) | 2008-06-12 | — | — | WO | disclosed |