⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16425666 | 0.79 | — | — | |
| SCHEMBL3663109 | 0.77 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL16984724 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL15259062 | 0.74 | — | — | |
| SCHEMBL1449319 | 0.74 | — | — | |
| SCHEMBL14406272 | 0.72 | ALDH1A1 (0.30) | — | |
| SCHEMBL13554077 | 0.72 | TSHR (0.39) | — | |
| SCHEMBL16984639 | 0.71 | — | — | |
| SCHEMBL18569831 | 0.70 | — | — | |
| SCHEMBL19851541 | 0.69 | DPP4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640422-B1 | POLYMERIC CONJUGATES OF ACTIVE PRINCIPLES, THEIR PROCESS OF PREPARATION AND THEIR POLYMERIC INTERMEDIATES | SANOFI SA (FR) | 2017-03-01 | — | — | EP | disclosed |
| US-9278137-B2 | Polymeric conjugates of active principles, their process of preparation and their polymeric intermediates | SANOFI (FR) | 2016-03-08 | — | — | US | disclosed |
| US-20130243719-A1 | POLYMERIC CONJUGATES OF ACTIVE PRINCIPLES, THEIR PROCESS OF PREPARATION AND THEIR POLYMERIC INTERMEDIATES | SANOFI (FR) | 2013-09-19 | — | — | US | disclosed |
| WO-2012066117-A1 | POLYMERIC CONJUGATES OF ACTIVE PRINCIPLES, THEIR PROCESS OF PREPARATION AND THEIR POLYMERIC INTERMEDIATES | SANOFI (FR) | 2012-05-24 | — | — | WO | disclosed |