Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15442929 | 0.93 | PKM (0.42) | PKMADRA2ATLR8KDM4ELMNA | |
| SCHEMBL23731047 | 0.88 | PKM (0.39) | PKMADRA2ATLR8PSEN1PSEN2 | |
| SCHEMBL17124813 | 0.86 | PKM (0.40) | PKMTLR8PSEN1PSEN2APH1B | |
| SCHEMBL12184971 | 0.81 | PSEN1 (0.37) | ADRA2ATLR8PSEN1PSEN2APH1B | |
| SCHEMBL9988363 | 0.81 | PSEN1 (0.37) | ADRA2ATLR8PSEN1PSEN2APH1B | |
| SCHEMBL14015488 | 0.81 | PSEN1 (0.43) | ADRA2ATLR8PSEN1PSEN2APH1B | |
| SCHEMBL15274951 | 0.81 | PSEN1 (0.37) | ADRA2ATLR8PSEN1PSEN2APH1B | |
| SCHEMBL4584716 | 0.81 | PSEN1 (0.37) | ADRA2ATLR8PSEN1PSEN2APH1B | |
| SCHEMBL20978319 | 0.81 | PSEN1 (0.37) | ADRA2ATLR8PSEN1PSEN2APH1B | |
| SCHEMBL15274946 | 0.81 | PSEN1 (0.37) | ADRA2ATLR8PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318894-B2 | Charged polymers and their uses in electronic devices | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-11-27 | — | — | US | disclosed |
| US-20120130025-A1 | CHARGED POLYMERS AND THEIR USES IN ELECTRONIC DEVICES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-05-24 | — | — | US | disclosed |