Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.74 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031906 | 0.88 | ESR1 (0.74) | ESR1ESR2HDAC6APP | |
| SCHEMBL27090228 | 0.87 | ESR1 (0.96) | ESR1ESR2NPC1RAB9AAPP | |
| SCHEMBL2158317 | 0.86 | ESR1 (1.00) | ESR1ESR2NPC1RAB9AAPP | |
| SCHEMBL24038264 | 0.81 | ESR1 (0.51) | ESR1ESR2NPC1RAB9AHDAC6 | |
| SCHEMBL2248809 | 0.80 | ESR1 (0.81) | ESR1ESR2NPC1RAB9AAPP | |
| SCHEMBL17561646 | 0.80 | ESR1 (0.81) | ESR1ESR2NPC1RAB9A | |
| SCHEMBL9114641 | 0.80 | ESR1 (0.81) | ESR1ESR2NPC1RAB9AHDAC6 | |
| SCHEMBL16894055 | 0.80 | ESR1 (0.81) | ESR1ESR2NPC1RAB9AAPP | |
| SCHEMBL31278592 | 0.80 | GPR119 (0.52) | ESR1ESR2NPC1RAB9AHDAC6 | |
| SCHEMBL8034090 | 0.80 | ESR1 (0.81) | ESR1ESR2NPC1RAB9AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696001-A | DETECTION OF HYDROLASES | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| US-5648229-A | DETECTION OF HYDROLYTIC ENZYMES | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |
| US-5585247-A | FLUORESCENT DYES FOR ENZYME IMMUNOASSAY | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| EP-0399409-A2 | Fluorogene compounds and their use | BEHRINGWERKE Aktiengesellschaft (DE) | 1990-11-28 | — | — | EP | disclosed |