Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740204 | 0.91 | HCAR2 (0.41) | NFE2L2HCAR2KEAP1ALDH1A1TDP1 | |
| SCHEMBL8740155 | 0.91 | HCAR2 (0.41) | NFE2L2HCAR2KEAP1ALDH1A1TDP1 | |
| SCHEMBL28362080 | 0.91 | HCAR2 (0.41) | NFE2L2HCAR2KEAP1ALDH1A1TDP1 | |
| SCHEMBL9245048 | 0.87 | HCAR2 (0.54) | NFE2L2HCAR2KEAP1ALDH1A1MAPT | |
| SCHEMBL9245045 | 0.87 | HCAR2 (0.54) | NFE2L2HCAR2KEAP1ALDH1A1MAPT | |
| SCHEMBL8740175 | 0.83 | HCAR2 (0.45) | NFE2L2HCAR2KEAP1ALDH1A1MAPT | |
| SCHEMBL16466651 | 0.82 | HCAR2 (0.50) | NFE2L2HCAR2KEAP1ALDH1A1MAPT | |
| SCHEMBL11226261 | 0.82 | HCAR2 (0.50) | NFE2L2HCAR2KEAP1ALDH1A1MAPT | |
| SCHEMBL65753 | 0.82 | TSHR (0.35) | NFE2L2HCAR2KEAP1ALDH1A1TDP1 | |
| SCHEMBL8740152 | 0.82 | TSHR (0.35) | NFE2L2HCAR2KEAP1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644004-A | Multi-component ethylenically unsaturated peroxyesters | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5420173-A | Curing unsaturated polyesters and peroxyester compositions | ARKEMA INC. | 1995-05-30 | — | — | US | disclosed |