SCHEMBL11226261

SCHEMBL11226261

CC(C)(C)OOC(=O)/C=C\C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.50
TSHR P16473 4/20 0.41
TP53 P04637 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.41
ALDH1A1 P00352 5/20 0.39
TDP1 Q9NUW8 3/20 0.39
HSD17B10 Q99714 3/20 0.39
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
ALOX15 P16050 2/20 0.33
RECQL P46063 2/20 0.33
GAA P10253 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16466651 1.00 HCAR2 (0.50) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL3878187 1.00 HCAR2 (0.50) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL28362080 0.91 HCAR2 (0.41) HCAR2TSHRALDH1A1TDP1HSD17B10
SCHEMBL8740204 0.91 HCAR2 (0.41) HCAR2TSHRALDH1A1TDP1HSD17B10
SCHEMBL8740155 0.91 HCAR2 (0.41) HCAR2TSHRALDH1A1TDP1HSD17B10
SCHEMBL8167945 0.87 HCAR2 (0.46) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL399610 0.87 HCAR2 (0.46) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL399609 0.87 HCAR2 (0.46) HCAR2TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL2804945 0.83 TSHR (0.53) HCAR2TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL9380769 0.83 TSHR (0.53) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026097214-A1 MODIFIED VINYLIDENE FLUORIDE POLYMER, PREPARATION METHOD THEREFOR, AND USE THEREOF 万华化学(烟台)电池产业有限公司 2026-05-15 WO claimed
CN-122010833-A Method for catalyzing tension ring heteroaryl by iron 南京师范大学 2026-05-12 CN claimed
CN-122011713-A High-performance LCP resin and preparation method thereof 红钰电子材料(无锡)有限公司 2026-05-12 CN claimed
US-20260071010-A1 RHEOLOGY MODIFYING OF POLYMERS WITH A RADICAL INITIATOR AND THIOURETHANE BASF SE (DE) 2026-03-12 US claimed
EP-3807229-B1 PROCESS FOR THE PRODUCTION OF COMPOSITE ARTICLES NOURYON CHEMICALS INT BV (NL) 2025-10-22 EP claimed
CN-116217431-B Encapsulation composition, encapsulation material, preparation method thereof and electronic device assembly 浙江巨化新材料研究院有限公司 2025-04-18 CN claimed
CN-119855855-A Rheology modification of polymers with free radical initiators and thiourethanes 巴斯夫欧洲公司 2025-04-18 CN claimed
CN-119816529-A Free radical curable acrylate polyol resin composition for making quartz-based artificial stone with improved UV radiation and weatherability A&A绿色凤凰集团股份有限公司 2025-04-11 CN claimed
CN-119591796-A Acrylic artificial stone particle board adopting mould pressing technology and preparation method thereof 广东热浪新材料科技有限公司 2025-03-11 CN claimed
CN-119431644-A Modified vinylidene fluoride polymer and preparation method and application thereof 万华化学(烟台)电池产业有限公司 2025-02-14 CN claimed
CN-115043963-A High-solid-content polyvinylidene fluoride dispersion liquid and preparation method and application thereof 万华化学(四川)电池材料科技有限公司 2022-09-13 CN claimed
CN-111138657-B Terpolymer resin 温州大学 2022-09-09 CN claimed
CN-114920868-A Fluoropolymer capable of improving adhesive force, preparation process and application 万华化学(四川)电池材料科技有限公司 2022-08-19 CN claimed
CN-114920867-A Vinylidene fluoride copolymer with controllable particle size distribution and preparation method thereof 万华化学(四川)有限公司 2022-08-19 CN claimed
CN-114805043-A Preparation method and system of cyclopentanone 中国石油化工股份有限公司 2022-07-29 CN claimed
CN-112587257-B Preparation method of denture overlay and denture overlay prepared by same 胡可辉 2022-07-19 CN claimed
CN-109790276-B Process for preparing elastomers 科思创德国股份有限公司 2022-06-10 CN claimed
CN-111117136-B Cable material 温州大学 2022-06-07 CN claimed
US-11312812-B2 Process for producing elastomers COVESTRO DEUTSCHLAND AG (DE) 2022-04-26 US claimed
EP-2321102-B1 PROCESS FOR THE PREPARATION OF CONGLOMERATE STONE ARTICLES, COMPRISING THE USE OF A PEROXIDE INITIATOR TONCELLI LUCA (IT) 2018-03-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071010-A1 RHEOLOGY MODIFYING OF POLYMERS WITH A RADICAL INITIATOR AND THIOURETHANE NOX1, CBR1, NOS1 HCAR2 3494/4885TSHR 3557/4885TP53 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.