⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95981 | 0.76 | TP53 (0.47) | — | |
| SCHEMBL78432 | 0.76 | TP53 (0.47) | — | |
| SCHEMBL9715475 | 0.75 | — | — | |
| SCHEMBL990356 | 0.73 | — | — | |
| SCHEMBL20593290 | 0.73 | TP53 (0.44) | — | |
| Ammonia Solution, Strong SCHEMBL8958635 | 0.73 | TP53 (0.44) | — | |
| SCHEMBL8688833 | 0.73 | — | — | |
| SCHEMBL11317937 | 0.73 | TP53 (0.44) | — | |
| SCHEMBL8691719 | 0.73 | — | — | |
| Hydrogen Sulfide SCHEMBL9001004 | 0.73 | TP53 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701446-A4 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1997-04-23 | — | — | EP | claimed |
| EP-0701446-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-20 | — | — | EP | claimed |
| WO-1994027627-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-08 | — | — | WO | claimed |
| EP-0701446-A4 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1997-04-23 | — | — | EP | disclosed |
| EP-0701446-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-20 | — | — | EP | disclosed |
| US-5459236-A | Hypertensive agents | FERRING AB (SE) | 1995-10-17 | — | — | US | disclosed |
| WO-1994027627-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |
| EP-0380554-B1 | VASOACTIVE PEPTIDES | Ferring AB (SE) | 1993-07-07 | — | — | EP | disclosed |
| EP-0380554-A1 | VASOACTIVE PEPTIDES. | FERRING AB (SE) | 1990-08-08 | — | — | EP | disclosed |
| WO-1989003393-A1 | VASOACTIVE PEPTIDES | FERRING AB (SE) | 1989-04-20 | — | — | WO | disclosed |