Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8958635

CC(SSC(C)C(=O)O)C(=O)O.N.N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.39
LMNA P02545 2/20 0.37
KDM4E B2RXH2 1/20 0.37
SLC7A5 Q01650 2/20 0.36
GABRR1 P24046 2/20 0.32
RNPEP Q9H4A4 1/20 0.32
CYP1A2 P05177 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95981 0.97 TP53 (0.47) TP53ALDH1A1HSD17B10LMNAKDM4E
Hydrogen Sulfide SCHEMBL9001004 0.93 TP53 (0.44) TP53ALDH1A1HSD17B10LMNAKDM4E
SCHEMBL11317937 0.93 TP53 (0.44) TP53ALDH1A1HSD17B10LMNAKDM4E
Acetic Acid SCHEMBL6932728 0.90 FFAR3 (0.44) TP53ALDH1A1HSD17B10LMNAKDM4E
Acetic Acid SCHEMBL20593502 0.88 FFAR3 (0.41) TP53ALDH1A1HSD17B10LMNAKDM4E
SCHEMBL16303293 0.85 TP53 (0.38) TP53ALDH1A1HSD17B10LMNAKDM4E
SCHEMBL5086037 0.84 TP53 (0.42) TP53ALDH1A1HSD17B10LMNAKDM4E
SCHEMBL22836201 0.83 SLC7A5 (0.42) TP53ALDH1A1HSD17B10LMNAKDM4E
SCHEMBL9715475 0.81
SCHEMBL1641494 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5520909-A WATER SOLUBLE DISULFIDES AND MERCAPTAN REDUCING AGENTS FOR RELAXING HAIR CONAIR CORPORATION (US) 1996-05-28 US claimed