SCHEMBL8740466

SCHEMBL8740466

C=C(C)C(=O)OC.[SiH3]O[SiH3]

nearest known ligand 0.88

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.88
TSHR P16473 4/20 0.46
TDP1 Q9NUW8 2/20 0.38
THRB P10828 1/20 0.38
HSD17B10 Q99714 1/20 0.35
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
MAPT P10636 1/20 0.32
TET2 Q6N021 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ELANE P08246 1/20 0.31
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4390490 0.94 ALDH1A1 (1.00) ALDH1A1TSHRTDP1THRBHSD17B10
SCHEMBL1849 0.94
SCHEMBL10636466 0.94
SCHEMBL2168919 0.91
SCHEMBL8627821 0.91
Ethylene SCHEMBL44117 0.91
Hydrogen Peroxide SCHEMBL9143793 0.91
SCHEMBL20681605 0.91
SCHEMBL21340366 0.91
Methyl Alcohol SCHEMBL1272141 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670770-A4 A METHOD OF MANUFACTURING A CONTACT LENS. PILKINGTON VISIONCARE INC (US) 1997-08-20 EP disclosed
EP-0670770-A1 A METHOD OF MANUFACTURING A CONTACT LENS PILKINGTON BARNES HIND, INC. (US) 1995-09-13 EP disclosed
US-5433898-A Multifocal PILKINGTON BARNES HIND, INC. (US) 1995-07-18 US disclosed
WO-1994006621-A9 A METHOD OF MANUFACTURING A CONTACT LENS 1994-05-26 WO disclosed
WO-1994006621-A1 A METHOD OF MANUFACTURING A CONTACT LENS PILKINGTON VISIONCARE INC. (US) 1994-03-31 WO disclosed
US-4046577-A PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS THE RICHARDSON COMPANY (US) 1977-09-06 US disclosed