Ethylene

Ethylene

SCHEMBL8740481

C=C.C=CCC(=O)OCCOC(=O)CC=C

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.47
TSHR P16473 6/20 0.41
ALDH1A1 P00352 5/20 0.41
TP53 P04637 2/20 0.41
HIF1A Q16665 2/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP3A4 P08684 2/20 0.36
GAA P10253 1/20 0.36
THRB P10828 2/20 0.34
TDP1 Q9NUW8 2/20 0.33
DGKA P23743 1/20 0.33
HPGD P15428 1/20 0.32
ADRA2A P08913 1/20 0.31
ADRA1A P35348 1/20 0.31
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33704 0.97 HTT (0.49) HTTTSHRALDH1A1TP53HIF1A
SCHEMBL5457043 0.90 HTT (0.45) HTTTSHRALDH1A1TP53HIF1A
Vinyl Chloride SCHEMBL11178409 0.90 HTT (0.45) HTTTSHRALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL11790538 0.88 HTT (0.47) HTTTSHRALDH1A1TP53HIF1A
SCHEMBL27486544 0.87 HTT (0.54) HTTTSHRALDH1A1TP53HIF1A
SCHEMBL5697728 0.87 HTT (0.59) HTTTSHRALDH1A1TP53HIF1A
SCHEMBL11571052 0.86 HTT (0.42) HTTTSHRALDH1A1TP53HIF1A
SCHEMBL13038458 0.86 ALDH1A1 (0.45) HTTTSHRALDH1A1TP53HIF1A
SCHEMBL28640670 0.86 HTT (0.42) HTTTSHRALDH1A1TP53HIF1A
SCHEMBL7226186 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0695223-A4 HEAT REACTIVATABLE ADHESIVE ASHLAND OIL INC (US) 1997-12-10 EP claimed
EP-0695223-A1 HEAT REACTIVATABLE ADHESIVE ASHLAND OIL, INC. (US) 1996-02-07 EP claimed
WO-1995019231-A1 HEAT REACTIVATABLE ADHESIVE ASHLAND OIL, INC. (US) 1995-07-20 WO claimed