Ethylene Glycol

Ethylene Glycol

SCHEMBL8740543

C=C(C)C(=O)OCCOC(=O)C(=C)C.OCCO.OCCO

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.65
TSHR P16473 6/20 0.57
ALDH1A1 P00352 6/20 0.46
TDP1 Q9NUW8 3/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
HSD17B10 Q99714 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL57404 1.00 THRB (0.65) THRBTSHRALDH1A1TDP1POLB
Ethylene Glycol SCHEMBL9462587 0.93 THRB (0.59) THRBTSHRALDH1A1TDP1POLB
Methacrylic Acid SCHEMBL3918766 0.93 THRB (0.59) THRBTSHRALDH1A1TDP1POLB
Ethylene Glycol SCHEMBL7267519 0.93 THRB (0.59) THRBTSHRALDH1A1TDP1POLB
Butane SCHEMBL5094524 0.93 THRB (0.64) THRBTSHRALDH1A1TDP1POLB
Ethylene Glycol SCHEMBL8659233 0.93 THRB (0.70) THRBTSHRALDH1A1TDP1POLB
Ethylene Glycol SCHEMBL27656717 0.93 THRB (0.57) THRBTSHRALDH1A1TDP1POLB
Ethylene Glycol SCHEMBL27569562 0.93 THRB (0.57) THRBTSHRALDH1A1TDP1POLB
SCHEMBL7623060 0.93 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
SCHEMBL6142874 0.92 THRB (0.74) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708801-A4 COATING AND WEARLAYER COMPOSITIONS FOR SURFACE COVERINGS CONGOLEUM CORP (US) 1997-07-02 EP disclosed
EP-0708801-A1 COATING AND WEARLAYER COMPOSITIONS FOR SURFACE COVERINGS CONGOLEUM CORPORATION (US) 1996-05-01 EP disclosed
WO-1994028067-A1 COATING AND WEARLAYER COMPOSITIONS FOR SURFACE COVERINGS CONGOLEUM CORPORATION (US) 1994-12-08 WO disclosed
US-5247035-A Diallyl ether copolymers formed by free radical polymerization BASF AKTIENGESELLSCHAFT (DE) 1993-09-21 US disclosed