Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1881515 | 0.98 | MAPT (0.69) | MAPTNPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL2134110 | 0.98 | MAPT (0.69) | MAPTNPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL6894653 | 0.85 | MAPT (0.66) | MAPTNPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL11970671 | 0.85 | MAPT (0.66) | MAPTNPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL6894661 | 0.85 | MAPT (0.66) | MAPTNPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL11970674 | 0.85 | MAPT (0.66) | MAPTNPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL29051547 | 0.85 | MAPT (0.66) | MAPTNPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL7941711 | 0.85 | SMN1; SMN2 (0.64) | MAPTNPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL10944710 | 0.85 | SMN1; SMN2 (0.64) | MAPTNPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL7941715 | 0.85 | SMN1; SMN2 (0.64) | MAPTNPC1RAB9AKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746410-A4 | WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CALIFORNIA INST OF TECHN (US) | 1997-04-09 | — | — | EP | disclosed |
| EP-0746410-A1 | WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995022405-A1 | WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1995-08-24 | — | — | WO | disclosed |