Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735897 | 0.83 | NPSR1 (0.41) | MAPTGLO1ALDH1A1LMNANPSR1 | |
| SCHEMBL8583434 | 0.82 | NPSR1 (0.55) | MAPTGLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8583432 | 0.82 | NPSR1 (0.55) | MAPTGLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10153090 | 0.81 | CYP2C9 (0.49) | MAPTGLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10656434 | 0.78 | NPSR1 (0.43) | MAPTGLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6729528 | 0.78 | NPSR1 (0.43) | MAPTGLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL4660722 | 0.78 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAGAAHCAR2 | |
| SCHEMBL2334064 | 0.78 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAGAAHCAR2 | |
| SCHEMBL2334069 | 0.78 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAGAAHCAR2 | |
| SCHEMBL8081528 | 0.77 | EGLN1 (0.44) | MAPTGLO1ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746410-A4 | WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CALIFORNIA INST OF TECHN (US) | 1997-04-09 | — | — | EP | disclosed |
| EP-0746410-A1 | WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995022405-A1 | WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1995-08-24 | — | — | WO | disclosed |