SCHEMBL8740662

SCHEMBL8740662

c1ccc(CC2CC3CCN2CC3)cc1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.66
CHRNA7 P36544 1/20 0.66
CHRNA4 P43681 1/20 0.66
GAA P10253 1/20 0.57
ALPG P10696 1/20 0.57
GFER P55789 1/20 0.57
GRIN2B Q13224 3/20 0.47
SLC18A3 Q16572 1/20 0.45
CCR3 P51677 1/20 0.44
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1950993 0.90 GAA (0.67) CHRNB2CHRNA7CHRNA4GAAALPG
Hydrochloric Acid SCHEMBL8864197 0.88 GAA (0.57) CHRNB2CHRNA7CHRNA4GAAALPG
SCHEMBL1950614 0.87 CHRNB2 (0.64) CHRNB2CHRNA7CHRNA4GAAALPG
SCHEMBL1952643 0.82 CHRNB2 (0.54) CHRNB2CHRNA7CHRNA4GAAALPG
SCHEMBL27887177 0.81 GAA (0.58) CHRNB2CHRNA7CHRNA4GAAALPG
SCHEMBL27901892 0.81 CHRNB2 (0.67) CHRNB2CHRNA7CHRNA4GAAALPG
SCHEMBL7041910 0.81 GFER (0.58) CHRNB2CHRNA7CHRNA4GAAALPG
SCHEMBL7045470 0.81 GAA (0.58) CHRNB2CHRNA7CHRNA4GAAALPG
SCHEMBL3223016 0.81 SLC18A2 (0.53) CHRNB2CHRNA7CHRNA4
SCHEMBL7042385 0.80 CHRNB2 (0.56) CHRNB2CHRNA7CHRNA4GAAALPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0746529-A4 ZEOLITE SSZ-42 CHEVRON USA INC (US) 1997-02-05 EP disclosed
EP-0746529-A1 ZEOLITE SSZ-42 CHEVRON U.S.A. INC. (US) 1996-12-11 EP disclosed
WO-1995022507-A1 ZEOLITE SSZ-42 CHEVRON U.S.A. INC. (US) 1995-08-24 WO disclosed