SCHEMBL8740849

SCHEMBL8740849

O=C(Cl)CSC(c1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 3/20 0.58
SLC6A4 P31645 2/20 0.58
PDPK1 O15530 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2577789 0.91 SLC6A3 (0.61) SLC6A3SLC6A4
SCHEMBL10334603 0.88 PDPK1 (0.60) SLC6A3SLC6A4PDPK1
SCHEMBL8675119 0.86 SLC6A3 (0.53) SLC6A3SLC6A4
SCHEMBL6074896 0.82 SLC6A3 (0.65) SLC6A3SLC6A4PDPK1
SCHEMBL14375775 0.81 SLC6A3 (0.88) SLC6A3SLC6A4
SCHEMBL6075052 0.80 SLC6A3 (0.54) SLC6A3SLC6A4
SCHEMBL6075209 0.77 SLC6A3 (0.68) SLC6A3SLC6A4
SCHEMBL6075154 0.77 SLC6A4 (0.51) SLC6A3SLC6A4
SCHEMBL2577670 0.76 SLC6A3 (0.65) SLC6A3SLC6A4PDPK1
SCHEMBL6075152 0.76 SLC6A3 (0.50) SLC6A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5667936-A FLUOROMETHYLATED HYDRAZIDE, HIGH CONTRAST, PROCESSING STABILITY, PRESERVABILITY FUJI PHOTO FILM CO., LTD. (JP) 1997-09-16 US disclosed
EP-0736798-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1996-10-09 EP disclosed