Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22548162 | 0.76 | BRD4 (0.70) | BRD4ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL22116110 | 0.76 | BRD4 (0.69) | PTK2BRD4CREBBP | |
| SCHEMBL19323971 | 0.74 | KDM4E (0.48) | BRD4KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL24263869 | 0.73 | BRD4 (0.67) | BRD4KDM4ECREBBPALDH1A1KMT2A | |
| SCHEMBL8153549 | 0.72 | PTK2 (0.62) | PTK2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL22548401 | 0.72 | BRD4 (0.66) | BRD4KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL18190690 | 0.71 | ALDH1A1 (0.46) | PTK2BRD4KDM4ECREBBPALDH1A1 | |
| SCHEMBL16090245 | 0.71 | USP2 (0.34) | PTK2BRD4KDM4ECREBBPALDH1A1 | |
| SCHEMBL19323689 | 0.69 | KDM4E (0.50) | BRD4KDM4ECREBBPALDH1A1KMT2A | |
| SCHEMBL4471381 | 0.68 | HCAR2 (0.34) | PTK2ALDH1A1KMT2AHCAR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684950-A4 | CHEMICAL COMPOUNDS USEFUL IN PHOTODYNAMIC THERAPY AND PRODUCTION OF LASER LIGHT. | BO DEKK VENTURES LTD (US) | 1997-10-15 | — | — | EP | disclosed |
| EP-0684950-A1 | CHEMICAL COMPOUNDS USEFUL IN PHOTODYNAMIC THERAPY AND PRODUCTION OF LASER LIGHT | BO-DEKK VENTURES, LTD. (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5446157-A | Boron difluoride compounds useful in photodynamic therapy and production of laser light | BO-DEKK VENTURES, LTD. | 1995-08-29 | — | — | US | disclosed |
| WO-1994019355-A1 | CHEMICAL COMPOUNDS USEFUL IN PHOTODYNAMIC THERAPY AND PRODUCTION OF LASER LIGHT | BO-DEKK VENTURES, LTD. (US) | 1994-09-01 | — | — | WO | disclosed |