Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.63 |
| ▸ | CCKAR | P32238 | 11/20 | 0.63 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.57 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866450 | 0.88 | CCKBR (0.66) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL9866463 | 0.88 | CCKBR (0.66) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL9866460 | 0.88 | CCKBR (0.66) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL643257 | 0.86 | CCKBR (0.64) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL643277 | 0.84 | CCKBR (0.68) | CCKBRCCKAR | |
| SCHEMBL24490741 | 0.83 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL20867074 | 0.83 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL18394863 | 0.82 | CCKBR (0.76) | CCKBRCCKAR | |
| SCHEMBL2930364 | 0.82 | CCKBR (0.76) | CCKBRCCKAR | |
| SCHEMBL18394473 | 0.82 | CCKBR (0.76) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760813-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0760813-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032191-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1995-11-30 | — | — | WO | disclosed |