SCHEMBL874203

SCHEMBL874203

Oc1ncnc(O)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1628118 0.84
SCHEMBL2492993 0.78
SCHEMBL2324216 0.76 FEN1 (0.30)
SCHEMBL3166412 0.74
SCHEMBL15649401 0.74 PDXK (0.31)
SCHEMBL1627372 0.69 HTT (0.43)
SCHEMBL1939076 0.69
SCHEMBL9427930 0.69
SCHEMBL2115437 0.69
SCHEMBL2232292 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109646793-B Transurethral prostate expanding catheter and expanding method thereof 江苏长寿棒科技有限公司 2024-08-20 CN claimed
CN-109925589-B Novel prostate expands and splits pipe 江苏长寿棒科技有限公司 2021-09-21 CN claimed
EP-1515954-B1 METHOD FOR PRODUCING 4,6-DICHLORO-5-FLUOROPYRIMIDINE BAYER CROPSCIENCE AG (DE) 2010-02-24 EP claimed
US-7129353-B2 Method for producing 4,6-dichloro-5-fluoropyrimidine BAYER CROPSCIENCE AG (DE) 2006-10-31 US claimed
US-20060014952-A1 Method for producing 4,6-dichloro-5-fluoropyrimidine BAYER INTELLECTUAL PROPERTY GMBH (DE) 2006-01-19 US claimed
EP-1515954-A1 METHOD FOR PRODUCING 4,6-DICHLORO-5-FLUOROPYRIMIDINE Bayer CropScience AG (DE) 2005-03-23 EP claimed
WO-2003106432-A1 METHOD FOR PRODUCING 4,6-DICHLORO-5-FLUOROPYRIMIDINE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-12-24 WO claimed
US-12559483-B2 Process for the preparation of fluoxastrobin and intermediates thereof UPL LTD (IN) 2026-02-24 US disclosed
EP-4605394-A1 PYRIMIDINE SGC STIMULATORS Tisento Therapeutics Inc. (US) 2025-08-27 EP disclosed
CN-109646793-B Transurethral prostate expanding catheter and expanding method thereof 江苏长寿棒科技有限公司 2024-08-20 CN disclosed
WO-2024086179-A1 PYRIMIDINE SGC STIMULATORS TISENTO THERAPEUTICS, INC. (US) 2024-04-25 WO disclosed
EP-3303312-B1 PROCESS FOR PREPARING (E)-(5,6-DIHYDRO-1,4,2-DIOXAZINE-3-YL)(2-HYDROXYPHENYL)METHANONE O-METHYL OXIME ARYSTA LIFESCIENCE CORP (JP) 2023-07-19 EP disclosed
EP-3303312-B1 PROCESS FOR PREPARING (E)-(5,6-DIHYDRO-1,4,2-DIOXAZINE-3-YL)(2-HYDROXYPHENYL)METHANONE O-METHYL OXIME ARYSTA LIFESCIENCE CORP (JP) 2023-07-19 EP disclosed
WO-2003106432-A1 METHOD FOR PRODUCING 4,6-DICHLORO-5-FLUOROPYRIMIDINE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-12-24 WO disclosed
US-6255486-B1 REACTING 2-FLUOROPROPANEDIOIC ACID, DIALKYLESTER WITH ETHYL/ METHYL FLUOROMALONATE &amp; FORMAMIDE IN PRESENCE OF ALKALI METAL ALKOXIDES, THEN WITH PHOSPHOROUS OXYCHLORIDE AND CHLORINE IN PRESENCE OF PHOSPHOROUS TRICHLORIDE, PHOSPHATE-FREE BAYER AKTIENGESELLSCHAFT (DE) 2001-07-03 US disclosed
JP-2001072667-A PRODUCTION OF 4,6-DICHLORO-5-FLUOROPYRIMIDINE BAYER AG 2001-03-21 JP disclosed
EP-1077210-A2 Preparation of 4,6-dichloro-5-fluorpyrimidine and its use as biocidally active agent Bayer Aktiengesellschaft (DE) 2001-02-21 EP disclosed
EP-1077210-A2 Preparation of 4,6-dichloro-5-fluorpyrimidine and its use as biocidally active agent Bayer Aktiengesellschaft (DE) 2001-02-21 EP disclosed
EP-0970057-A2 SUBSTITUTED AMINOSALICYCLIC ACID AMIDES WITH FUNGICIDAL EFFECT AND INTERMEDIATE PRODUCTS FOR PRODUCTION THEREOF BAYER AG (DE) 2000-01-12 EP disclosed
WO-1998041513-A2 SUBSTITUTED AMINOSALICYCLIC ACID AMIDES WITH FUNGICIDAL EFFECT AND INTERMEDIATE PRODUCTS FOR PRODUCTION THEREOF BAYER AKTIENGESELLSCHAFT (DE) 1998-09-24 WO disclosed