Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27576158 | 0.84 | KDM4E (0.46) | POLBL3MBTL1KDM4ECA12CA1 | |
| SCHEMBL8517391 | 0.77 | NEU3 (0.39) | KDM4EMAPTGAAAPAF1MEN1 | |
| SCHEMBL9013756 | 0.75 | KMT2A (0.49) | POLBL3MBTL1MAPTGAAAPAF1 | |
| SCHEMBL11732266 | 0.74 | CA12 (0.57) | POLBL3MBTL1KDM4ECA12CA1 | |
| SCHEMBL741752 | 0.73 | NPSR1 (0.64) | POLBL3MBTL1MAPTGAAAPAF1 | |
| SCHEMBL6825878 | 0.73 | MEN1 (0.50) | POLBL3MBTL1KDM4ECA12CA1 | |
| SCHEMBL8034169 | 0.71 | PTPN1 (0.50) | CA12CA1CA2CA9CA4 | |
| SCHEMBL8044893 | 0.71 | NPSR1 (0.61) | POLBL3MBTL1APAF1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8550497 | 0.71 | NPSR1 (0.61) | POLBL3MBTL1MAPTGAAAPAF1 | |
| SCHEMBL8742107 | 0.71 | TPMT (0.49) | KDM4EMEN1KMT2ATSHRHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755372-A4 | INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE AND METHODS OF MAKING AND USING THE SAME | UNIV ALABAMA (US) | 1997-09-10 | — | — | EP | disclosed |
| EP-0755372-A1 | INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE AND METHODS OF MAKING AND USING THE SAME | THE UNIVERSITY OF ALABAMA AT BIRMINGHAM (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028376-A1 | INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE AND METHODS OF MAKING AND USING THE SAME | THE UNIVERSITY OF ALABAMA AT BIRMINGHAM (US) | 1995-10-26 | — | — | WO | disclosed |