Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.62 |
| ▸ | RPA1 | P27694 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 3/20 | 0.58 |
| ▸ | MARS1 | P56192 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742262 | 1.00 | CNR1 (0.62) | CNR1RPA1CNR2MARS1MEN1 | |
| SCHEMBL17203783 | 0.96 | CNR1 (0.67) | CNR1RPA1CNR2MARS1MEN1 | |
| SCHEMBL8742182 | 0.81 | CNR1 (0.62) | CNR1RPA1CNR2MARS1MEN1 | |
| SCHEMBL17203717 | 0.79 | RPA1 (0.56) | CNR1RPA1CNR2MARS1MEN1 | |
| SCHEMBL17204151 | 0.78 | RPA1 (0.54) | CNR1RPA1CNR2MARS1MEN1 | |
| SCHEMBL7351242 | 0.78 | CNR1 (0.68) | CNR1RPA1MARS1MEN1LMNA | |
| SCHEMBL2871062 | 0.77 | RPA1 (1.00) | CNR1RPA1MARS1MEN1LMNA | |
| SCHEMBL8197517 | 0.77 | RPA1 (0.80) | CNR1RPA1CNR2MARS1MEN1 | |
| Hydrochloric Acid SCHEMBL9155041 | 0.77 | CNR1 (0.67) | CNR1RPA1MARS1MEN1LMNA | |
| SCHEMBL3095089 | 0.77 | CNR1 (0.53) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6073014-A | — | — | None | — | — | JP | disclosed |
| US-5624941-A | Pyrazole derivatives, method of preparing them and pharmaceutical compositions in which they are present | SANOFI (FR) | 1997-04-29 | — | — | US | disclosed |
| EP-0576357-B1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1997-03-05 | — | — | EP | disclosed |
| JP-H0673014-A | NEW PYRAZOLE DERIVATIVE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING IT | ELF SANOFI | 1994-03-15 | — | — | JP | disclosed |
| EP-0576357-A1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1993-12-29 | — | — | EP | disclosed |