Ethylene Glycol

Ethylene Glycol

SCHEMBL8742258

C=Cc1ccncc1.OCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
JUN P05412 1/20 0.40
NFKB1 P19838 1/20 0.40
TSHR P16473 1/20 0.40
SNCA P37840 1/20 0.39
CYP19A1 P11511 2/20 0.38
CYP11B2 P19099 2/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 4/20 0.35
ALOX5 P09917 1/20 0.35
HDAC8 Q9BY41 1/20 0.34
KDM1A O60341 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
HPGD P15428 2/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP1A2 P05177 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL29118531 0.88 ALDH1A1 (0.43) ALDH1A1JUNNFKB1TSHRSNCA
Hydrogen Peroxide SCHEMBL27481776 0.87 ALDH1A1 (0.53) ALDH1A1JUNNFKB1TSHRSNCA
SCHEMBL14867 0.87
SCHEMBL28222778 0.87 ALDH1A1 (0.59) ALDH1A1JUNNFKB1TSHRCYP19A1
Methyl Alcohol SCHEMBL28761443 0.85 ALDH1A1 (0.50) ALDH1A1JUNNFKB1TSHRSNCA
SCHEMBL9405395 0.85
SCHEMBL11007081 0.85
SCHEMBL1462870 0.85
Hydrochloric Acid SCHEMBL220696 0.85
SCHEMBL9693194 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104174388-B A kind of metal organic frame composite and preparation method thereof FUDAN UNIVERSITY (CN) 2016-04-13 CN claimed
CN-104174388-A Metal organic frame composite material and preparation method thereof UNIV FUDAN 2014-12-03 CN claimed
EP-0612241-A4 IONIC BEADS USEFUL FOR CONTROLLED RELEASE AND ADSORPTION. ADVANCED POLYMER SYSTEMS INC (US) 1997-03-05 EP claimed
EP-0612241-A1 IONIC BEADS USEFUL FOR CONTROLLED RELEASE AND ADSORPTION Advanced Polymer Systems, Inc. (US) 1994-08-31 EP claimed
WO-1993007862-A1 IONIC BEADS USEFUL FOR CONTROLLED RELEASE AND ADSORPTION ADVANCED POLYMER SYSTEMS, INC. (US) 1993-04-29 WO claimed
CN-104174388-B A kind of metal organic frame composite and preparation method thereof FUDAN UNIVERSITY (CN) 2016-04-13 CN disclosed
CN-104174388-A Metal organic frame composite material and preparation method thereof UNIV FUDAN 2014-12-03 CN disclosed