Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.66 |
| ▸ | CTSS | P25774 | 1/20 | 0.66 |
| ▸ | CTSK | P43235 | 1/20 | 0.66 |
| ▸ | ACE | P12821 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CCKBR | P32239 | 6/20 | 0.59 |
| ▸ | REN | P00797 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30638855 | 0.89 | ACE (0.78) | CTSLCTSSCTSKACEMAPT | |
| SCHEMBL27885190 | 0.89 | ACE (0.78) | CTSLCTSSCTSKACEMAPT | |
| SCHEMBL27885189 | 0.89 | ACE (0.78) | CTSLCTSSCTSKACEMAPT | |
| SCHEMBL3825352 | 0.89 | ACE (0.78) | CTSLCTSSCTSKACEMAPT | |
| SCHEMBL31484559 | 0.89 | ACE (0.78) | CTSLCTSSCTSKACEMAPT | |
| SCHEMBL29401065 | 0.88 | CTSL (0.63) | CTSLCTSSCTSKACEHDAC3 | |
| SCHEMBL29398124 | 0.88 | CTSL (0.63) | CTSLCTSSCTSKACEHDAC3 | |
| SCHEMBL3560147 | 0.88 | CTSL (0.63) | CTSLCTSSCTSKACEHDAC3 | |
| SCHEMBL6409052 | 0.88 | CTSL (0.63) | CTSLCTSSCTSKACEHDAC3 | |
| SCHEMBL6833548 | 0.88 | CTSL (0.63) | CTSLCTSSCTSKACEHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783489-A1 | ALDEHYDE DERIVATIVES AS UPSTEINE PROTEASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010014-A1 | ALDEHYDE DERIVATIVES AS UPSTEINE PROTEASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-04 | — | — | WO | disclosed |