Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742471 | 1.00 | RAB9A (0.62) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8742485 | 1.00 | RAB9A (0.62) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8742454 | 1.00 | RAB9A (0.62) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8742604 | 1.00 | RAB9A (0.62) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8742521 | 1.00 | RAB9A (0.62) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9331485 | 1.00 | RAB9A (0.62) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8742580 | 1.00 | RAB9A (0.62) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8742528 | 1.00 | RAB9A (0.62) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8742529 | 1.00 | RAB9A (0.62) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8742502 | 1.00 | RAB9A (0.62) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309514-B2 | MEDIA CONTAINING DERIVATIVES OF THIAZOLE AND THIADIAZOLE, WITH SMECTIC LIQUID-CRYSTAL PHASE | MERCK PATENT GMBH (DE) | 1997-10-15 | — | — | EP | disclosed |
| US-5478496-A | Media containing thiazole derivatives and thiadiazole derivatives and having a smectic liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-26 | — | — | US | disclosed |
| EP-0309514-B1 | MEDIA CONTAINING DERIVATIVES OF THIAZOLE AND THIADIAZOLE, WITH SMECTIC LIQUID-CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1992-12-02 | — | — | EP | disclosed |
| EP-0309514-A1 | MEDIA CONTAINING DERIVATIVES OF THIAZOLE AND THIADIAZOLE, WITH SMECTIC LIQUID-CRYSTAL PHASE. | MERCK PATENT GMBH (DE) | 1989-04-05 | — | — | EP | disclosed |
| WO-1988008019-A1 | MEDIA CONTAINING DERIVATIVES OF THIAZOLE AND THIADIAZOLE, WITH SMECTIC LIQUID-CRYSTAL PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-20 | — | — | WO | disclosed |