Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 19/20 | 1.00 |
| ▸ | AVPR1B | P47901 | 16/20 | 1.00 |
| ▸ | AVPR2 | P30518 | 11/20 | 1.00 |
| ▸ | OXTR | P30559 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991283 | 0.86 | AVPR1A (1.00) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6986830 | 0.86 | AVPR1A (0.75) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6988528 | 0.86 | AVPR1A (1.00) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6989046 | 0.86 | AVPR1A (1.00) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL8796814 | 0.83 | AVPR1A (0.77) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6989132 | 0.82 | AVPR1A (0.85) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL4146200 | 0.82 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL5945610 | 0.82 | AVPR2 (0.76) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL8883555 | 0.81 | AVPR1A (0.76) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6993669 | 0.80 | AVPR1A (0.79) | AVPR1AAVPR1BAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696112-A | TREATMENT OF CONGESTIVE HEART FAILURE, CORONARY VASOCONSTRICTION | AMERICAN CYANAMID COMPANY (US) | 1997-12-09 | — | — | US | claimed |
| JP-9020779-A | — | — | None | — | — | JP | disclosed |
| JP-H0920779-A | CONDENSED FIVE-MEMBERED HETEROCYCLIC AZEPINE COMPOUND AND ITS MEDICINAL USE | JAPAN TOBACCO INC | 1997-01-21 | — | — | JP | disclosed |