Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.58 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGFR | P43088 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743003 | 1.00 | TBXA2R (0.58) | TBXA2RPTGER2LTB4RPTGER4PTGER3 | |
| SCHEMBL27868603 | 0.93 | TBXA2R (0.50) | TBXA2RPTGER2PTGER1PTGFR | |
| SCHEMBL6512170 | 0.93 | TBXA2R (0.50) | TBXA2RPTGER2PTGER1PTGFR | |
| SCHEMBL2743522 | 0.93 | TBXA2R (0.50) | TBXA2RPTGER2PTGER1PTGFR | |
| SCHEMBL21358345 | 0.87 | FOLH1 (0.46) | TBXA2RFFAR1 | |
| SCHEMBL641514 | 0.87 | FOLH1 (0.46) | TBXA2RFFAR1 | |
| SCHEMBL67664 | 0.86 | TBXA2R (0.65) | TBXA2R | |
| SCHEMBL9308449 | 0.84 | TBXAS1 (0.58) | TBXA2RLTB4RFFAR4FFAR1 | |
| SCHEMBL6907990 | 0.84 | TBXAS1 (0.58) | TBXA2RLTB4RFFAR4FFAR1 | |
| SCHEMBL6907995 | 0.84 | TBXAS1 (0.58) | TBXA2RLTB4RFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751113-A1 | Optically active phenol derivatives and preparation thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5420363-A | Catalytic reaction of phenol with secondary carbinol for enantiomorphs | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5354913-A | Chemical intermediates for drugs or drugs as thromboxane, prostaglandin antagonist, lipoxygenase enzyme inhibitor, antioxidants | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0582382-A2 | Optically active phenol derivatives and preparation thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-02-09 | — | — | EP | disclosed |