Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28782473 | 0.86 | BACE1 (0.56) | LMNAHTTMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL3234553 | 0.86 | KDM4E (0.53) | LMNAMAPK1TUBB4ATUBBTUBA3C | |
| SCHEMBL29019507 | 0.83 | LMNA (0.49) | LMNAHTTMAPK1RAB9ATUBB1 | |
| SCHEMBL153056 | 0.83 | CA12 (0.59) | LMNAMAPK1TUBB4ATUBBTUBA3C | |
| SCHEMBL2729632 | 0.81 | TSHR (0.64) | MAPK1RAB9ASMN1; SMN2TUBB4ATUBB | |
| SCHEMBL3236668 | 0.81 | KDM4E (0.46) | LMNAHTTRAB9AKDM4EMEN1 | |
| SCHEMBL28365704 | 0.81 | LMNA (0.50) | LMNAHTTMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL31621879 | 0.81 | LMNA (0.52) | LMNAMAPK1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL823757 | 0.81 | LMNA (0.52) | LMNAMAPK1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL14451171 | 0.80 | KMT2A (0.60) | LMNAHTTMAPK1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368090-A | Compounds as Immunomodulators | 百时美施贵宝公司 | 2018-08-03 | — | — | CN | claimed |
| CN-106714770-A | Hydroxysteroid compounds, intermediates thereof, preparation method, composition and uses thereof | 斯法尔制药私人有限公司 | 2017-05-24 | — | — | CN | claimed |
| EP-2536733-A1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | Boehringer Ingelheim International GmbH (DE) | 2012-12-26 | — | — | EP | claimed |
| CN-102371718-A | Decorative film and decorative device | SIPIX CHEMICAL INC | 2012-03-14 | — | — | CN | claimed |
| WO-2011101424-A1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-25 | — | — | WO | claimed |
| CN-1324027-C | Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives | SAMSUNG ELECTRONICS CO LTD (KR) | 2007-07-04 | — | — | CN | claimed |
| EP-0973791-A2 | PROCESS FOR PREPARATION OF 7 ALPHA-CARBOXYL 9, 11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN AND A GENERAL PROCESS FOR THE EPOXIDATION OF OLIFINIC DOUBLE BONDS | G.D. Searle & Co. (US) | 2000-01-26 | — | — | EP | claimed |
| WO-1997021720-A2 | PROCESSES FOR PREPARATION OF 7 ALPHA-CARBOXYL 9,11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN AND A GENERAL PROCESS FOR THE EPOXIDATION OF OLIFINIC DOUBLE BONDS | G.D. SEARLE AND CO. (US) | 1997-06-19 | — | — | WO | claimed |
| US-20230348441-A1 | BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR | MEDSHINE DISCOVERY INC. (CN) | 2023-11-02 | — | — | US | disclosed |
| CN-116589454-A | Aromatic heterocyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-08-15 | — | — | CN | disclosed |
| EP-3986392-A2 | COMPOUNDS FOR TREATMENT OF PD-L1 DISEASES | ChemoCentryx, Inc. (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-109503686-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-108314697-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-108546277-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-1998025948-A9 | PROCESSES FOR PREPARATION OF 9,11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN | — | 1998-11-19 | — | — | WO | disclosed |
| CN-1034807-C | Bromate as inhibitor of nitrosamine formation for nitrate stabilized isothiazolones and process | ROHM & HAAS (US) | 1997-05-07 | — | — | CN | disclosed |
| CN-1131288-A | Electronic photographic method | MITA INDUSTRIAL CO LTD (JP) | 1996-09-18 | — | — | CN | disclosed |
| CN-1131285-A | Electrophotographic method using photosensitive material | MITA INDUSTRIAL CO LTD (JP) | 1996-09-18 | — | — | CN | disclosed |
| CN-1081436-A | Method for synthesizing diphenyl sulfide tetracarboxylic acid and derivative | CHANGCHUN APPLIED CHEMISTRY (CN) | 1994-02-02 | — | — | CN | disclosed |
| CN-1071921-A | Be used for suppressing to be formed the bromate and the method for nitrosamine by nitrate stabilized isothiazolones | ROHM & HAAS (US) | 1993-05-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348441-A1 | BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR | CRBN, CRKL, NCOR1 | LMNA 3513/4885HTT 3097/4885MAPK1 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.