Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CDK9 | P50750 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19501652 | 0.85 | TGM2 (0.85) | TGM2TP53EPHX1TSHREPHX2 | |
| SCHEMBL81209 | 0.84 | TGM2 (1.00) | TGM2TP53EPHX1TSHREPHX2 | |
| SCHEMBL29111221 | 0.83 | TGM2 (0.75) | TGM2TP53EPHX1TSHREPHX2 | |
| SCHEMBL30211836 | 0.82 | TGM2 (0.96) | TGM2TP53EPHX1TSHREPHX2 | |
| SCHEMBL28240522 | 0.82 | TGM2 (0.96) | TGM2TP53EPHX1TSHREPHX2 | |
| SCHEMBL11239798 | 0.81 | TGM2 (0.73) | TGM2SMN1; SMN2NPC1RAB9AF13A1 | |
| SCHEMBL13134385 | 0.81 | MDM2 (0.62) | TGM2EPHX1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL10401175 | 0.81 | SMN1; SMN2 (0.80) | TP53EPHX1TSHREPHX2CDK9 | |
| SCHEMBL19501015 | 0.80 | TGM2 (0.70) | TGM2TP53EPHX1TSHREPHX2 | |
| SCHEMBL19501282 | 0.80 | TGM2 (0.76) | TGM2TP53EPHX1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751119-A1 | A process for preparing acryloyl carbamates or ureas | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-4332821-A | FUNGICIDES | ABBOTT LABORATORIES (US) | 1982-06-01 | — | — | US | disclosed |