Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.76 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743193 | 1.00 | TBXA2R (0.76) | TBXA2RSLC6A3FABP4KCNH2TBXAS1 | |
| SCHEMBL9507218 | 0.91 | TBXA2R (0.76) | TBXA2RSLC6A3FABP4KCNH2TBXAS1 | |
| SCHEMBL9066613 | 0.89 | TBXA2R (0.65) | TBXA2RFABP4TBXAS1 | |
| SCHEMBL9508154 | 0.87 | TBXA2R (0.74) | TBXA2RSLC6A3FABP4KCNH2TBXAS1 | |
| SCHEMBL8742842 | 0.83 | TBXA2R (0.75) | TBXA2RSLC6A3KCNH2TBXAS1LMNA | |
| SCHEMBL8742836 | 0.83 | TBXA2R (0.75) | TBXA2RSLC6A3KCNH2TBXAS1LMNA | |
| SCHEMBL9699510 | 0.82 | TBXA2R (0.82) | TBXA2RSLC6A3KCNH2TBXAS1LMNA | |
| SCHEMBL8742924 | 0.82 | TBXA2R (0.73) | TBXA2RSLC6A3KCNH2TBXAS1LMNA | |
| SCHEMBL8742915 | 0.82 | TBXA2R (0.73) | TBXA2RSLC6A3KCNH2TBXAS1LMNA | |
| SCHEMBL8743288 | 0.81 | TBXA2R (0.80) | TBXA2RSLC6A3KCNH2TBXAS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751113-A1 | Optically active phenol derivatives and preparation thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5420363-A | Catalytic reaction of phenol with secondary carbinol for enantiomorphs | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5354913-A | Chemical intermediates for drugs or drugs as thromboxane, prostaglandin antagonist, lipoxygenase enzyme inhibitor, antioxidants | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0582382-A2 | Optically active phenol derivatives and preparation thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-02-09 | — | — | EP | disclosed |