Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.76 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508154 | 0.92 | TBXA2R (0.74) | TBXA2RSLC6A3FABP4KCNH2TBXAS1 | |
| SCHEMBL8743182 | 0.91 | TBXA2R (0.76) | TBXA2RSLC6A3FABP4KCNH2TBXAS1 | |
| SCHEMBL8743193 | 0.91 | TBXA2R (0.76) | TBXA2RSLC6A3FABP4KCNH2TBXAS1 | |
| SCHEMBL9698250 | 0.87 | TBXA2R (0.58) | TBXA2RSLC6A3KCNH2LMNAFOLH1 | |
| SCHEMBL8742842 | 0.83 | TBXA2R (0.75) | TBXA2RSLC6A3KCNH2TBXAS1LMNA | |
| SCHEMBL8742836 | 0.83 | TBXA2R (0.75) | TBXA2RSLC6A3KCNH2TBXAS1LMNA | |
| SCHEMBL9699510 | 0.82 | TBXA2R (0.82) | TBXA2RSLC6A3KCNH2TBXAS1LMNA | |
| SCHEMBL8743288 | 0.81 | TBXA2R (0.80) | TBXA2RSLC6A3KCNH2TBXAS1LMNA | |
| SCHEMBL8743202 | 0.81 | TBXA2R (0.80) | TBXA2RSLC6A3KCNH2TBXAS1LMNA | |
| SCHEMBL8743215 | 0.81 | TBXA2R (0.80) | TBXA2RSLC6A3KCNH2TBXAS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2152940-A | — | — | None | — | — | JP | disclosed |
| EP-0295037-B1 | PHENOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| EP-0537954-A1 | Process of preparing diphenylmethane derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-5162571-A | Phenol derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| JP-H02152940-A | PHENOL DERIVATIVE, PRODUCTION THEREOF AND MEDICINE COMPOSITION CONTAINING THE SAME | TAKEDA CHEM IND LTD | 1990-06-12 | — | — | JP | disclosed |
| EP-0295037-A2 | Phenol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-12-14 | — | — | EP | disclosed |