Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29486481 | 0.94 | TYR (0.50) | CASRTYRCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL439493 | 0.94 | TYR (0.50) | CASRTYRCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL28682080 | 0.94 | TYR (0.50) | CASRTYRCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL9418446 | 0.91 | CASR (0.46) | CASRTYRCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL5605959 | 0.89 | CASR (0.47) | CASRTYRCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL2846227 | 0.82 | LMNA (0.50) | TYRLMNASMN1; SMN2ESR1 | |
| SCHEMBL6225152 | 0.81 | CACNA2D1 (0.41) | CASRCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL11130635 | 0.81 | CASR (0.45) | CASRTYRCACNA2D1CACNA1BCACNB1 | |
| Ammonia Solution, Strong SCHEMBL10808062 | 0.80 | LMNA (0.48) | TYRLMNASMN1; SMN2ESR1 | |
| SCHEMBL11881999 | 0.80 | ESR1 (0.54) | CASRTYRCACNA1CLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448538-A1 | Improved glyphosate formulations | MONSANTO COMPANY (US) | 1991-09-25 | — | — | EP | claimed |
| EP-0448538-B1 | Improved glyphosate formulations | MONSANTO CO (US) | 1997-01-02 | — | — | EP | disclosed |
| EP-0448538-A1 | Improved glyphosate formulations | MONSANTO COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |