SCHEMBL8743277

SCHEMBL8743277

CCCCCCCCCCCCC12OC1O2

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.44
ALDH1A1 P00352 3/20 0.37
DNM1 Q05193 7/20 0.36
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC22A1 O15245 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8671830 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL18632072 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL8743092 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11580672 0.83 TSHR (0.61) TSHRALDH1A1
SCHEMBL23854647 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA
Hexadecane SCHEMBL23499901 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11854960 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA
Decane SCHEMBL23499900 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA
Decane SCHEMBL170135 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA
Hexadecane SCHEMBL2039121 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0535930-B1 Thermoreversible recording material, thermoreversible recording medium and recording method OKI ELECTRIC IND CO LTD (JP) 1997-01-02 EP disclosed
US-5310611-A Comprising polyvinyl acetal matrix and low molecular weight organic compound; transparency change with heat history OKI ELECTRIC INDUSTRY CO., LTD. (JP) 1994-05-10 US disclosed
EP-0535930-A1 Thermoreversible recording material, thermoreversible recording medium and recording method Oki Electric Industry Co., Ltd. (JP) 1993-04-07 EP disclosed