SCHEMBL8743372

SCHEMBL8743372

CC=C(CCOC)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 5/20 0.49
ALDH1A1 P00352 1/20 0.41
GRIK1 P39086 1/20 0.39
GRIK2 Q13002 1/20 0.39
TSHR P16473 3/20 0.33
DDAH1 O94760 1/20 0.32
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29697202 0.82 APEX1 (0.46) APEX1ALDH1A1TSHRDDAH1
SCHEMBL27995943 0.79 APEX1 (0.37) APEX1ALDH1A1TSHRKDM4E
SCHEMBL28396306 0.79 GRIK1 (0.48) ALDH1A1GRIK1GRIK2TSHRKDM4E
SCHEMBL3241555 0.77 APEX1 (0.43) APEX1ALDH1A1
SCHEMBL3241550 0.77 APEX1 (0.43) APEX1ALDH1A1
SCHEMBL16956789 0.75
SCHEMBL3281805 0.74 APEX1 (0.41) APEX1ALDH1A1
SCHEMBL28396333 0.74 GRIK1 (0.44) APEX1GRIK1GRIK2TSHRKDM4E
SCHEMBL11329510 0.72 ALDH1A1 (0.46) APEX1ALDH1A1TSHRDDAH1KDM4E
SCHEMBL11720742 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408429-B1 Triblock copolymers containing at least one acrylic block, a process for their preparation and their application in the manufacture of elastomer products ATOCHEM ELF SA (FR) 1997-01-02 EP disclosed
WO-1991000874-A1 ACRYLIC TRISEQUENCED COPOLYMERS, THEIR PREPARATION AND APPLICATION TO THE PRODUCTION OF ELASTOMER ARTICLES ATOCHEM (FR) 1991-01-24 WO disclosed
EP-0408429-A1 Triblock copolymers containing at least one acrylic block, a process for their preparation and their application in the manufacture of elastomer products ELF ATOCHEM S.A. (FR) 1991-01-16 EP disclosed