⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519076 | 0.92 | — | — | |
| SCHEMBL15062197 | 0.90 | ALDH1A1 (0.40) | — | |
| SCHEMBL13649507 | 0.90 | ALDH1A1 (0.40) | — | |
| SCHEMBL2530269 | 0.90 | ALDH1A1 (0.40) | — | |
| SCHEMBL10565094 | 0.83 | — | — | |
| SCHEMBL5473091 | 0.77 | BRD4 (0.42) | — | |
| SCHEMBL10869 | 0.77 | — | — | |
| SCHEMBL7805829 | 0.77 | — | — | |
| SCHEMBL3239145 | 0.77 | — | — | |
| SCHEMBL649628 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546008-A | Hollow carbon fiber reinforced carbon aerogel composite material and preparation method and application thereof | 东华大学 | 2024-08-27 | — | — | CN | claimed |
| CN-117897392-A | Aqueous solid phase peptide synthesis | 多肽实验室(PPL)控股公司 | 2024-04-16 | — | — | CN | claimed |
| CN-115960007-A | Preparation method of sitagliptin intermediate by using nitrogen-containing formyl catalyst | 浙江大学 | 2023-04-14 | — | — | CN | claimed |
| EP-3356375-B1 | PROCESS FOR RECOVERING A MIXTURE COMPRISING A (THIO)PHOSPHORIC ACID DERIVATIVE | BASF SE (DE) | 2023-01-04 | — | — | EP | claimed |
| CN-110997670-A | [1,2,4] triazolo [4,3-a ] pyridyl substituted indole compounds | 百时美施贵宝公司 | 2020-04-10 | — | — | CN | claimed |
| US-9834548-B2 | Pyridazine compounds as JAK inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2017-12-05 | — | — | US | claimed |
| US-20170174673-A1 | PYRIDAZINE COMPOUNDS AS JAK INHIBITORS | ALEXION PHARMACEUTICALS, INC. | 2017-06-22 | — | — | US | claimed |
| EP-2949644-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | Paratek Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | claimed |
| WO-2015123453-A1 | PYRIDAZINE COMPOUNDS AS JAK INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2015-08-20 | — | — | WO | claimed |
| US-20140309192-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC, | 2014-10-16 | — | — | US | claimed |
| EP-1807387-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | Paratek Pharmaceuticals, Inc. (US) | 2007-07-18 | — | — | EP | claimed |
| US-20060166945-A1 | Substituted tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2006-07-27 | — | — | US | claimed |
| WO-2006047756-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. (US) | 2006-05-04 | — | — | WO | claimed |
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | claimed |
| EP-1086949-B1 | Process for the preparation of isochroman-3-ones | CLARIANT GMBH (DE) | 2003-02-19 | — | — | EP | claimed |
| WO-1996032403-A2 | NOVEL CYTOSINE AND CYTIDINE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-10-17 | — | — | WO | claimed |
| US-4863903-A | RENIN ENZYME INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | claimed |
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | claimed |
| EP-0144290-A2 | Substituted ethylenediamine derivatives | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | claimed |
| EP-0037990-B1 | PHENYL QUINOLIZIDINES, CORRESPONDING PHARMACEUTICAL PREPARATIONS, THE PREPARATION OF THE ACTIVE COMPOUNDS AND CORRESPONDING STARTING COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-12-05 | — | — | EP | claimed |