Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154167 | 0.87 | ACE2 (0.33) | TSHR | |
| SCHEMBL9794175 | 0.87 | ACE2 (0.33) | TSHR | |
| SCHEMBL9794469 | 0.87 | ACE2 (0.33) | TSHR | |
| SCHEMBL11652442 | 0.83 | — | — | |
| SCHEMBL28899820 | 0.79 | — | — | |
| SCHEMBL235075 | 0.78 | — | — | |
| SCHEMBL14986356 | 0.78 | — | — | |
| SCHEMBL15283773 | 0.78 | — | — | |
| SCHEMBL10946888 | 0.77 | TSHR (0.42) | TSHR | |
| SCHEMBL28847735 | 0.76 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589965-B1 | ORGANOBORON REAGENTS FOR THE PREPARATION OF UNSUBSTITUTED PROPARGYLIC ALCOHOLS | MERRELL PHARMA INC (US) | 1997-01-08 | — | — | EP | disclosed |
| EP-0589965-A1 | NEW ORGANOBORON REAGENTS FOR THE PREPARATION OF UNSUBSTITUTED PROPARGYLIC ALCOHOLS. | MERRELL DOW PHARMA (US) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993000347-A1 | NEW ORGANOBORON REAGENTS FOR THE PREPARATION OF UNSUBSTITUTED PROPARGYLIC ALCOHOLS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-01-07 | — | — | WO | disclosed |
| US-5157167-A | Organoboron reagents for the preparation of unsubstituted propargylic alcohols | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-10-20 | — | — | US | disclosed |
| US-5110966-A | New organoboron reagents for the preparation unsubstituted propargylic alcohols | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-05-05 | — | — | US | disclosed |