Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794175 | 1.00 | ACE2 (0.33) | ACE2SPHK1ALDH1A1FDPSADRB2 | |
| SCHEMBL9794469 | 1.00 | ACE2 (0.33) | ACE2SPHK1ALDH1A1FDPSADRB2 | |
| SCHEMBL8743532 | 0.87 | TSHR (0.42) | TSHR | |
| SCHEMBL487493 | 0.80 | — | — | |
| SCHEMBL6137557 | 0.80 | — | — | |
| SCHEMBL11775465 | 0.80 | — | — | |
| SCHEMBL11652442 | 0.79 | — | — | |
| SCHEMBL1658455 | 0.75 | ACE2 (0.39) | ACE2SPHK1ALDH1A1FDPSADRB2 | |
| SCHEMBL873768 | 0.75 | ACE2 (0.39) | ACE2SPHK1ALDH1A1FDPSADRB2 | |
| SCHEMBL2504628 | 0.74 | DNM1 (0.43) | ACE2ALDH1A1FDPSTSHRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943607-B1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDINS | DAIICHI FINE CHEM CO LTD (JP) | 2005-01-26 | — | — | EP | disclosed |
| US-6313341-B1 | Process for the preparation of prostaglandins | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0943607-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDINS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-4983627-A | Treating atherosclerosis, thrombosis and vasospasms; anticholesterol,-secretory,-ulcer and hypotensive agents | SYNTEX (U.S.A.) INC. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0196617-B1 | [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same | SYNTEX (U.S.A.) INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4735966-A | ANTICOAGULANTS, VASODILATORS, HYPOTENSIVE AND ANTICHOLESTEROL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-04-05 | — | — | US | disclosed |
| EP-0257609-A2 | Novel substituted (4.2.0)Bicyclooctane derivatives with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1988-03-02 | — | — | EP | disclosed |
| US-4678805-A | Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0196617-A1 | [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same | SYNTEX (U.S.A.) INC. (US) | 1986-10-08 | — | — | EP | disclosed |
| US-4608388-A | Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1986-08-26 | — | — | US | disclosed |