Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 10/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743564 | 0.80 | BLM (0.57) | — | |
| SCHEMBL10756719 | 0.79 | HDAC6 (0.48) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL8743585 | 0.78 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL8743523 | 0.77 | HDAC6 (0.46) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL3854007 | 0.75 | HSP90AB1 (0.51) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL6884460 | 0.74 | HSP90AB1 (0.55) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL10918545 | 0.73 | HDAC6 (0.47) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL31058755 | 0.73 | HDAC6 (0.54) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL11033158 | 0.73 | HSP90AB1 (0.44) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL2916968 | 0.73 | HDAC6 (0.49) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335770-B1 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMA INC (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0339161-A1 | Novel fluorophosphonate nucleotide derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-11-02 | — | — | EP | disclosed |
| EP-0335770-A2 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1989-10-04 | — | — | EP | disclosed |