Ethylene

Ethylene

SCHEMBL8743643

C=C.OP(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.41
TSHR P16473 1/20 0.41
CA5A P35218 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
CA4 P22748 1/20 0.38
NR1H2 P55055 1/20 0.37
BAX Q07812 1/20 0.37
ALDH1A1 P00352 1/20 0.36
RECQL P46063 1/20 0.36
SRC P12931 1/20 0.36
KCNA3 P22001 1/20 0.35
ALOX15 P16050 1/20 0.34
TGM2 P21980 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
FFAR1 O14842 1/20 0.32
LMNA P02545 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132913 0.95 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL30883096 0.95 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
Fluoride SCHEMBL27692228 0.92 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL28345841 0.92 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
Phosphine SCHEMBL28033415 0.92 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL8978293 0.92 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
Hydrochloric Acid SCHEMBL9814237 0.92 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL7009097 0.92 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL28831578 0.92 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL10386425 0.92 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646146-B1 IMPROVED PROCESS FOR PREPARING EXTENDED CHAIN POLYESTERS AND BLOCK OR GRAFT COPOLYESTERS ALLIED SIGNAL INC (US) 1997-11-12 EP disclosed
EP-0651774-B1 PROCESS FOR PREPARING CHAIN EXTENDED POLYMERS AND GRAFT AND BLOCK COPOLYMERS ALLIED SIGNAL INC (US) 1997-01-08 EP disclosed
EP-0651774-A1 PROCESS FOR PREPARING CHAIN EXTENDED POLYMERS AND GRAFT AND BLOCK COPOLYMERS. ALLIED SIGNAL INC (US) 1995-05-10 EP disclosed
EP-0646146-A1 IMPROVED PROCESS FOR PREPARING EXTENDED CHAIN POLYESTERS AND BLOCK OR GRAFT COPOLYESTERS AlliedSignal Inc. (US) 1995-04-05 EP disclosed
US-5389721-A Using phosphorous(III)-containing chain extension reagents; heating; using no catalytic substances which contain elements from groups VA and VIA of the periodic table ALLIEDSIGNAL INC. (US) 1995-02-14 US disclosed
US-5326830-A Heterocyclic nitrogen-trivalent phosphorous compounds ALLIEDSIGNAL INC. (US) 1994-07-05 US disclosed
WO-1994010242-A1 NUCLEATING SYSTEM FOR POLYESTERS AND ARTICLES FORMED THEREFROM ALLIED-SIGNAL INC. (US) 1994-05-11 WO disclosed
WO-1994002537-A1 PROCESS FOR PREPARING CHAIN EXTENDED POLYMERS AND GRAFT AND BLOCK COPOLYMERS ALLIED-SIGNAL INC. (US) 1994-02-03 WO disclosed
WO-1993025601-A1 IMPROVED PROCESS FOR PREPARING EXTENDED CHAIN POLYESTERS AND BLOCK OR GRAFT COPOLYESTERS ALLIED-SIGNAL INC. (US) 1993-12-23 WO disclosed
US-4963311-A GRAFTING A PHOSPHITE-MODIFIED POLYESTER BASED ON A CARBO DIACID AND A CARBO OR ACYCLIC GLYCOL TO A NYLON; SPINNING AND DRAWING ALLIED-SIGNAL (US) 1990-10-16 US disclosed
US-4568720-A WITH PHOSPHITE COMPOUND ALLIED CHEMICAL CORPORATION (US) 1986-02-04 US disclosed