SCHEMBL8743993

SCHEMBL8743993

CCC(C(=O)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8744165 0.80 CHRM1 (0.37) TSHRFAAH
SCHEMBL17469430 0.79 CHRM1 (0.35) CYP2D6CYP2C9TSHRCYP2C19FAAH
SCHEMBL2035661 0.79 CHRM1 (0.35) CYP2D6CYP2C9TSHRCYP2C19FAAH
SCHEMBL7638052 0.77 CHRM1 (0.33) CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL14534529 0.77 CA1 (0.37) CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL10974017 0.77 CYP2D6 (0.32) CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL3473720 0.77 CA1 (0.37) CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL3971915 0.77 TSHR (0.32) CYP2D6CYP2C9TSHRCYP2C19
Hydrochloric Acid SCHEMBL28492070 0.77 CHRM1 (0.33) CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL28267785 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0753085-A1 PROCESS FOR PREPARING BRANCHED PERFLUOROCHEMICALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-15 EP disclosed
WO-1995026429-A1 PROCESS FOR PREPARING BRANCHED PERFLUOROCHEMICALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-10-05 WO disclosed