Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 6/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768953 | 0.85 | MEN1 (0.48) | HSD17B2 | |
| SCHEMBL6768951 | 0.85 | MEN1 (0.48) | HSD17B2 | |
| SCHEMBL6778355 | 0.84 | HSD17B2 (0.56) | HSD17B2 | |
| SCHEMBL6778353 | 0.84 | HSD17B2 (0.56) | HSD17B2 | |
| SCHEMBL8744100 | 0.81 | HSD17B2 (0.52) | HSD17B2 | |
| SCHEMBL10686321 | 0.78 | CA1 (0.57) | HSD17B2SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL8744078 | 0.74 | HSD17B2 (0.58) | HSD17B2 | |
| SCHEMBL6767810 | 0.74 | HSD17B2 (0.58) | HSD17B2 | |
| SCHEMBL7140657 | 0.74 | HSD17B2 (0.58) | HSD17B2 | |
| SCHEMBL6767812 | 0.74 | HSD17B2 (0.58) | HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246534-B1 | Optically pure 4,5-disubstituted gamma-butyrolactame enantiomers, process for their preparation and their use | BAYER AG (DE) | 1997-01-15 | — | — | EP | disclosed |
| US-4847287-A | Pure enantiomers of 4,5-disubstituted gamma-butyrolactams, and their use as antiamnestic agents | BAYER AG (DE) | 1989-07-11 | — | — | US | disclosed |