Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778353 | 0.86 | HSD17B2 (0.56) | HSD17B2SIGMAR1 | |
| SCHEMBL6778355 | 0.86 | HSD17B2 (0.56) | HSD17B2SIGMAR1 | |
| SCHEMBL8744053 | 0.81 | HSD17B2 (0.51) | HSD17B2 | |
| SCHEMBL6992826 | 0.78 | HSD17B2 (0.60) | HSD17B2 | |
| SCHEMBL6767884 | 0.78 | HSD17B2 (0.60) | HSD17B2 | |
| SCHEMBL6768953 | 0.77 | MEN1 (0.48) | HSD17B2 | |
| SCHEMBL6768951 | 0.77 | MEN1 (0.48) | HSD17B2 | |
| SCHEMBL6771119 | 0.76 | HSD17B2 (0.45) | HSD17B2 | |
| SCHEMBL9680139 | 0.72 | EPHX1 (0.41) | — | |
| SCHEMBL7140657 | 0.72 | HSD17B2 (0.58) | HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246534-B1 | Optically pure 4,5-disubstituted gamma-butyrolactame enantiomers, process for their preparation and their use | BAYER AG (DE) | 1997-01-15 | — | — | EP | disclosed |
| US-4847287-A | Pure enantiomers of 4,5-disubstituted gamma-butyrolactams, and their use as antiamnestic agents | BAYER AG (DE) | 1989-07-11 | — | — | US | disclosed |
| EP-0246534-A2 | Optically pure 4,5-disubstituted gamma-butyrolactame enantiomers, process for their preparation and their use | BAYER AG (DE) | 1987-11-25 | — | — | EP | disclosed |